
Industrial Statistical Consultant
Thomas Murphy - Industrial Statistical Consultant
Work History
| 2009 - Present | Senior Consultant |
D.H. Gold Associates, Inc. | |
Industrial Statistical Consultant |
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| 1995 - 2009 | Industrial Statistical Consultant
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Independent Consultant | |
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Independent consultant to the pharmaceutical, chemical, and consumer products industries. Analytical method development / quality control / validation, product fill weight control, analysis of stability studies to recommend shelf life and release limits for drug and consumer products, manufacturing quality control / procesS validation studies, advertising claim support, training courses in statistical applications. |
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| 1995 - 2001, 2005 | Quality Assurance Statistician (Temporary Employee) |
Wyeth-Ayerst Laboratories, Pearl River, NY |
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Process validation, analytical method validation, specification justification, training. |
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1990 - 1995 |
Principal Research Statistician |
American Cyanamid Company, Agricultural Research Division, Princeton, NJ |
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Internal statistical consultant in support of Agricultural Group operations, including research/development, analytical method development, animal drug safety / efficacy studies, and manufacturing. |
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| 1982 - 1990 | American Cyanamid Shulton (Consumer Products) Research Division, Clifton, NJ |
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1987 - 1990 Principal Research Statistician
1984 - 1987 Supervisor, Clinical Laboratory
1982 - 1984 Group Leader, Statistical & Information Services
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| 1967 - 1982 | American Cyanamid Shulton (Consumer Products) Chemical Research Division Bound Brook, NJ |
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1980 - 1982 Group Leader, Computers, Statistics and Instruments
1978 - 1980 Senior/ Principal Research Statistician
1974 - 1978 Group Leader, Automation and Statistical Analysis
1971 - 1974 Group Leader, Computer Control
1967 - 1971 Statistician |
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| 1962 - 1967 | Control Laboratory Supervisor |
Hercules, Incorporated , Parlin, NJ |
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Supervision of plant control laboratory (30+ lab operators and technicians) for polyethylene and acetic acid plants, plus plant troubleshooting and customer complaint calls. |
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| 1960 - 1962 |
Process Development Engineer |
Hercules, Incorporated , Parlin, NJ |
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Plant troubleshooting and process development in support of polyethylene manufacturing. |
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| 1959 - 1960 | Production Shift Supervisor |
Hercules, Incorporated , Franklin, VA |
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| Supervised shift operations (seven operators) of a chemical manufacturing plant. | |||
| 1957 - 1959 | Pilot Plant Engineer |
Wilmington, DE and Savannah, GA |
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Operated and supervised bench-scale and pilot-scale operations for new products in thermoplastics, insecticides, and paper chemicals. |
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Education
| 1957 | Bachelor of Science - Chemical Engineering |
University of Maryland |
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| 1964 | Master of Science - Applied Statistics |
Rutgers University |
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| 1965 - 1969 | Completed course work for Ph.D. program in Applied Statistics | Rutgers University
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Professional and Honorary Society Memberships:
- American Society for Testing and Materials - Fellow 1997
- Officer of E11 Committee on Quality & Statistics
- Chair, (2002-2003), Vice Chair (1996-2001, 2004-2005), Secretary (1992-1996)
- Chair of E11.03 Subcommittee on Stat. Analysis and Control Tech. (1987-1997)
- C hair of E11.70 Subcommittee on Editorial/Terminology (2002-2008)
- Chair of E11.30 Subcommittee on Statistical Quality Control (2008-2009)
- Chair of E11.20 Subcommittee on Test Method Evaluation and Quality Control (2010-present)
- Committee E02 on Terminology – Member (2004-2007)
- Committee E55 on Manufacture of Pharmaceutical Products – Member (2004 – present)
- Award of Merit 1997
- Frank W. Reinhardt Award (Terminology) 2008
- American Society for Quality - Fellow 1987
- US TAG to ISO/TC 69 / Z1 Statistics – member (2003-present), Vice Chair 2007-2008
- Chemical Division, Chair (1982-83), other offices (1978-82)
- Editorial Review Board Quality Progress (1983-89)
- Technometrics Management Committee (1984-86)
- Publications Review Board (1983-91)
- Ellis R. Ott Award (Metro Section ASQ) 2001
- American Statistical Association - Member
- Member, Youden Award Committee (1991-93, 1997-2003)
- New Jersey Chapter Symposium Committee (1995-98)
- American Institute of Chemical Engineers - Member
- Chair of New Jersey Section, (1969-70)
- Sigma Xi , national research society - Member
- Alpha Chi Sigma, national chemistry fraternity - Professional Member.
Publications:
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"Design and Analysis of Industrial Experiments", Chemical Engineering, 48, 168-182 (1977).
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"Experimental Design and Analysis", Chapter 13, Applied Techniques in Statistics for Selected Industries, H. E. Hill and J. W. Prane, eds., Wiley, (1984).
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"Experimental Design for Process Variability", with K. Sears, Transactions of the 39th Annual Quality Congress, American Society for Quality Control, 374-384 (1985).
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"Long and Short Range Precision in HPSEC", with L. Papazian, Journal of Liquid Chromatography, 13:1, 25-49 (1990).
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"Analysis of Antiperspirant Efficacy Test Results", with M. Levine, Journal of the Society of Cosmetic Chemists, 42:3, 167-197 (1991).
- "The Application of Response Surface Methodology to Sterilization Process Development and Validation of a Water Cascade Autoclave", with J. Hokes, T. Green and A. Cundell, PDA Journal of Pharmaceutical Science and Technology, 53:2, 83-94(1999).
- "Statistical Process Control and Process Capability", with M. Utter and S. Singh, Encyclopedia of Pharmaceutical Technology, (2003)
- "Response Surface Methodology for Validation of Oral Dosage Forms", Chapter 6, Pharmaceutical and Medical Device Validation by Experimental Design, L. Torbeck, ed., Informa Healthcare, (2007)
- "Reporting Test Results – Determining Significant Digits and Rounding Properly", with P. Fortini, ASTM Standardization News, September/October 2008.
- "Dealing with Outliers", with A. Lau, ASTM Standardization News, November/December 2008.
Papers Presented at Scientific Meetings
- "Ratio Estimation", 29th All Day Conference on QC and Statistics in Industry, (Metropolitan Section, ASQC), Edison, NJ, September, 1977.
- "Applications in Industrial Experimentation", 6th Annual ASQC Seminar on QC, (Delaware Section, ASQC), Newark, DE, March, 1979.
- "Factorial Design Tutorial", 31st All Day Conference on QC and Stat in Industry, (Metropolitan Section, ASQC), Edison, NJ, September, 1979.
- "Test Methodology in the Routine Control Laboratory", 23rd Annual Fall Technical Conference (Chemical Division, ASQC), Minneapolis, MN, November, 1979.
- "Experimental Design in Practice", 33rd All Day Conference on QC and Stat in Industry, (Metropolitan Section, ASQC), Newark, NJ, September, 1981.
- "Experimental Design", ASQC Tappan Zee Section Meeting, January, 1983.
- "Applications of Experimental Design", 5th Annual Conference on Quality in the Health Care Industries, (Biomedical Division, ASQC), New Brunswick, NJ, April, 1983.
- "Clinical Testing of Consumer Products", 12th Annual Symposium on Quality Control, (Delaware Section, ASQC), Newark, DE, March, 1985.
- "Controlling Process Variability", The Second Ellis R. Ott Conference on Quality Management and Statistics in Industry, New Brunswick, NJ March, 1985.
- "Experimental Design for Process Variability", 39th Annual Quality Congress, ASQC, Baltimore, MD, May, 1985.
- "Consumer Clinical Testing", 30th Annual Fall Technical Conference, (Chemical Division, ASQC), Charlotte, NC, October, 1986.
- "Statistical Methods for Clinical Testing", Dermal Clinical Evaluation Society, Newark, NJ, February, 1987.
- "Using ASTM Standard Practice E 691 for Conducting an Interlaboratory Test Program", Meeting of ASTM Committee C 16 on Thermal Insulation, Hartford, CT, October, 1989.
- "The Uses and Misuses of Taguchi Methods", Spring Conference, (North Jersey Section, ASQC), May, 1990.
- "Using ASTM Standard Practice E 691 for Conducting an Interlaboratory Test Program", Meeting of ASTM Committee C 37 on Thermal Analysis, Philadelphia, PA, March, 1992.
- "The Application of Response Surface Methodology to Sterilization Process Development and Validation of a Water Cascade Autoclave", WORLDPHARM99, 1999. FTC
- "The Application of Response Surface Methodology to Sterilization Process Development and Validation of a Water Cascade Autoclave", 48th Annual Fall Technical Conference, (ASQC/ASA), Roanoke, VA, October, 2004.
Company Presentatons:
- "Ridge Regression Explained", American Cyanamid Statistics Seminar, May, 1979.
- "What's Happening in Quality in the Chemical Process Industry", American Cyanamid Chemical Group SPC Seminar, Newark, NJ, February, 1987.
- "Design of Experiments Workshop", American Cyanamid Process Development Symposiums, 1980, 1984, 1987, 1991.
- "Design of Experiments", Presentation and Workshop, American Cyanamid Formulations Symposium, 1982.
- "Measurement Assurance Workshop", American Cyanamid Analytical Symposium, 1990.
- "Animal Drug Stability Testing", American Cyanamid Analytical Symposium, 1992.
Company publications:
- "Statistical Manual for Analytical Chemists", American Cyanamid Publication,
First Edition (1982), Third Edition (2000).
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